Abstract: The central laboratory for science and technology at general hospital explores research project orientation mode for experimental teaching through ESA (engage-study-activate) model with the expansion of postgraduate scale and the continuous improvement of experimental requirements. According to the characters of ESA model and the actual needs of research-oriented graduate students in medicine, the laboratory imports the laddered practical training method in order to inspire students' enthusiasm. The attempts not only enhances students' research skills, but also accelerates scientific output and contributes to the success of science research at general hospital, as well as proves its feasibility and validity.

Key words: Experimental teaching, Engage-study-activate model, Research project orientation, Laddered practical training