Abstract: Medical education in the new technological revolution, especially in the era of artificial intelligence, will undergo profound changes. The increasing public demand for health, complex and diverse health systems, medical education in the popularization stage, and continuously developing and updating medical knowledge all pose new challenges to the reform and development of medical education. This article reviews the process of the fourth education revolution triggered by the new technological revolution, and then proposes the concept and characteristics of the fourth generation of medical education reform in the context of the new technological revolution, especially artificial intelligence, after reviewing the reform process of the three generations of medical education. The article proposes that the fourth generation of medical education reform faces a new transformation from disease-centered to health-centered. The organizational model of medical education faces reconstruction, and the mechanism and system of medical education face significant changes. Updating the concept of medical education, innovating the talent training system guided by health needs, and establishing a new paradigm of medical education supported by artificial intelligence, which is health-centered and characterized by crossover, cross-border, and integration, has become the content of a new generation of medical education reform.

Key words: Medical education, Artificial intelligence, Paradigm transformation, Health-Centered, Cross-boundary, Cross-integration and Integration