Abstract: Objective To explore the influencing factors and management strategies of early participation in clinical research training for clinical medicine undergraduates, and to provide an empirical reference. Methods A questionnaire survey was implemented among 182 undergraduate students in grade 2019 to 2020 majoring in clinical medicine in Peking University Health Science Center from May to June 2022. Multivariate logistic regression model was used to explore factors affecting students' participation in early clinical research training. Results Compared with non-participants, participants had higher grades (OR=6.62, 95%CI: 2.75-15.90, P<0.001), higher proportion of interest in clinical research (OR=4.98, 95%CI: 1.47-16.92, P=0.010) and higher proportion of willingness to obtain research achievements (OR=3.69, 95%CI: 1.18-11.56, P=0.025). The 68 constructive suggestions put forward by students were mainly classified into 22 items (32.4%) of the project management, 13 items (19.1%) of guidance method and 12 items (17.6%) of time arrangement. Conclusions Grade, interest and research achievements are the main factors that influence the early participation of clinical medicine undergraduates in clinical research training. University affiliated hospitals should strengthen publicity and support toward lower grade level, stimulate students' interest, set reasonable goals, improve students' sense of gain and achievement, continue to encourage and support students to participate in clinical research training, and to promote the improvement of students' ability of clinical medicine research.

Key words: Students, medical, Clinical research training, Clinical medicine, Research ability, Influencing factors, Management strategies