Abstract: Objective To explore autonomous learning model of pathophysiology based on platform of Worlduc.com.Methods The questionnaire was implemented in the Grade 2012 of clinical medicine in Xiangnan University to understand the usage of Worlduc.com. The class 6-7 and 10-11 were randomly selected as the control and reform group respectively. The latter adopted autonomous learning mode based on Worlduc.com combination-integration, cooperation and communication. Students'examination were analyzed and questionnaire survey was carried out.Results 57.4%(251/437) of the students of clinical medicine used Worlduc.com for autonomous learning, but 39.8% (100/251) of them used it under the supervision of school or parents. 93.5%(100/107) of the students of the reform group accepted the teaching model, moreover, their learning achievement and ability of autonomous learning were significantly higher than those of the control group.Conclusions The model of Worlduc.com combination-integration, cooperation and communication can improve the ability of autonomous learning and be helpful to teach.

Key words: Worlduc.com, Group combination-integration, Cooperation and communication, Autonomous learning