Abstract: Objective To explore the method of case analysis combined with quantitative analysis to evaluate the capacity of medical graduates in recognizing and analyzing ethical issues. Methods Based on the ethical issues presented in stem cell therapy from clinical case,the questionnaire was distributed to 176 graduates enrolled in 2019 in Peking Union Medical College and the influencing factors of the questionnaire scores were analyzed with a self-designed scale. Results The general result was well. 89.8% (158/176) graduate students recognized the problems like inadequate informed consent from patients, unacceptable risk-benefit ratio, lack of responsibility, but 50.1%(90/176) of students failed to evaluate the weakness linking to ethical principles and just 35.2%(62/176) of them fully demonstrated informed consent status of patients. The multivariate logistic analysis showed thatfemale students are 3.36 times than male students to fully discuss the informed consent (OR=3.36,95%CI was 1.27 to 8.88). Conclusions Most graduates can recognize ethical issues, while the capacity of analysis need to be improved especially for male students in terms of gaining informed consent. Method of quantitative research in case analysis may evaluate the ethical capacity of graduates and provide scientific evidences for improving ethical education.

Key words: Ethical education, Quantitative research, Informed consent, Risk-benefit analysis, Stem cell therapy