Objective To explore the current status and development trend of clinical thinking research based on Web of Science (WOS). Methods Using the HistCite software, the literature from the WOS database established up to December 31, 2022 is taken as the research object. ″Clinical thinking″ or ″clinical reasoning″ are used as search keywords to analyze the number of related articles in the database, institutional distribution, research directions, and frontier topics, in order to outline the overall trend of research on clinical thinking. Results A total of 3,094 articles were retrieved. The research on clinical thinking can be roughly divided into three development stages: an initial stage (1966 to 1990, with an annual publication volume in single digits), a rising stage (1991 to 2011, with an annual publication volume between 50 and 100), and a steep rise stage (2012 to the present, with 341 articles published in 2022). The institution with the highest number of publications is McGill University in Canada, with the number of 80. High-frequency keywords include teaching, concordance, and script. The forefront topics of research are focused on the nature of clinical thinking, assessment of clinical thinking, and how to conduct clinical thinking teaching, with calls for the formulation of universal guidelines. Conclusions The volume of publications on clinical thinking research continues to grow. China has a low publication volume, with most publications coming from institutions in the United Kingdom and the United States. Research content mainly focuses on comprehensive analysis and reflection on clinical thinking, with insufficient empirical research. Specialized studies on scripts, teaching, and evaluation are gradually emerging. In the future, China should focus on theoretical research on clinical thinking, with emphasis on building teaching and evaluation systems for clinical thinking, as well as the application of emerging technologies in clinical thinking and the formulation of universal guidelines and standards. Additionally, efforts should be made to increase the international visibility and impact of research.
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