Abstract: This paper is to explore the combining theory and practice on training outstanding doctors, further to investigate the student-centered, ability-oriented and innovation ability teaching philosophy. During the course of teaching, problem-based learning (PBL) combined with theory teaching, case-based learning (CBL) combined with experimental teaching, epidemiological practice teaching combined with scientific research were applied. All these enable clinical medical students to master the basic concepts, basic principle and the method of epidemiology. The reformed curriculum made: the excellent rate of PBL learning reach76.8% (25/33); pass rate of final assessment for students raise from 87.9% (29/33) to 97.0% (32/33), final excellent rate reach about 30.3%(10/30). All these contribute to set up a solid foundation of using theoretical epidemiology for students’ future clinical and research work. Meanwhile, Epidemiology teaching in Tongji University won the excellent course of Shanghai, a group number of outstanding young teachers has been well trained.

Key words: Epidemiology, Problem-based learning, Case-based learning, Clinical medicine specialty, Curriculum reform