Abstract: Objective This paper explore the application and the effect of the clinical research course of Peking University People’s Hospital (PKUPH) in 8-year medical students at clinical medicine stage I. Methods Construct the course of clinical research at clinical medicine stage I of the 8-year medical students that entered college in 2013 majoring in clinical medicine, the course include the lecture and the practice. All the students learned the lecture together but choose the teacher as “former mentor” respectively. The effect of the clinical research training was evaluated by the questionnaire and the discussion. Results The students considered the clinical research course were important in helping completing the graduation thesis, cultivating clinical research method and ability, and increasing scientific research interest. Conclusions The course of clinical research in the early stage of the 8-year medical students is an effective method for improving the ability of the students to do clinical research and increasing scientific research interest. It’s important in cultivating high quality medical talents.

Key words: 8-year medical students, Clinical research ability, Construction, Application