Abstract: Objective To investigate the influence of graduate students in infectious disease teaching hospital on the knowledge of prevention and control of COVID-19 pandemic (referred to as the pandemic) and their willingness to participate in the fight against the pandemic. Methods In May 2020, 204 graduates from three infectious disease teaching hospitals affiliated to Capital Medical University were selected as the research objects, and relevant questionnaire surveys were conducted and then the results were analyzed by chi-square χ² test and multivariate logistic regression. Results There were 84.1% (159/189) of graduate students who took the initiative to learn about COVID-19 pandemic, and 70.4% (133/189) of them are willing to participate in the front-line anti-epidemic work. The understanding of infectious disease routine work can increase their initiative in learning knowledge related to COVID-19 pandemic prevention and control[OR (95%CI)=2.719 (1.170～6.323), P=0.020], and their daily learning time for the prevention and control knowledge is equal to or more than 30 minutes[OR (95%CI)=1.902 (1.041～3.475), P=0.037]. The students' willingness to participate in the front-line anti-epidemic work is a facilitating factor for supporting their learning of COVID-19 diagnosis and treatment guidelines[OR (95%CI)=2.904 (1.323～6.374), P=0.008]. The graduates who have studied the guidelines [OR(95%CI)=2.644(1.050～6.653), P=0.039] and have undergone positive changes in professional identity [OR(95%CI)=3.897(1.213～12.519), P=0.022] are more willing to participate in the front-line fight against the pandemic. However, students younger than 30 years old are less willing to participate in the fight against the pandemic than those who are 30 years or older[OR(95%CI)=0.281(0.080～0.995),P=0.049]. Conclusions Graduate students are able to actively learn knowledge about COVID-19 prevention and control, and a relatively high proportion of them are willing to participate in the front-line fight against the pandemic. Those who have studied the guide are more willing to participate in the first-line fight against the pandemic. Enhancing universal education for the prevention and control of infectious diseases may increase graduate students' enthusiasm for learning about disease prevention and control, young graduate students need more encouragement to improve their willingness to join clinical work related to COVID-19 infection control.

Key words: Graduate students, COVID-19 prevention and control, Willingness to fight the pandemic, COVID-19 pandemic