Objective To explore the effectiveness of patient-oriented health education in the pediatric training by eight-year program undergraduates. Methods From January to March in 2019, fifteen students from eight-year program of clinical medicine enrolled in 2014 who were intern in the general pediatric ward of Peking University Third Hospital were selected as the research objects to carry out collective health education for hospitalized children and their parents. A questionnaire survey was carried out to evaluate the outcome of health education among the students, children, parents and teachers and the Wilcoxon test is used to analyze the results. Results Before and after health education, the differences in the evaluation of health education in four aspects covering personal value[3.5 (2.3, 4.0) vs. 4.5 (3.8, 5.0), medical management[4.0 (2.5, 4.0) vs. 5.0(4.0, 5.0)],professional knowledge[3.8 (2.3, 4.0) vs. 4.8 (4.0, 5.0)]and comprehensive quality [3.8 (2.5, 4.0) vs. 5.0 (4.0, 5.0)] are statistically significant (P<0.05). The results also showed that 90.0% (63/70) of children and their parents believe health education is very effective in increasing health knowledge, 87.1% (61/70) of them believe that the education helps them in increasing compliance and trust in doctors. The teacher's overall score is 93.0 (85.0, 100), of which the accuracy score is the highest [25 .0(22.0, 25.0)], and the interesting score is the lowest [22 .0(20.0, 25.0)]. There are 86.2% (25/29) of teachers believe that health education is effective in consolidating students' theoretical knowledge and stimulated their learning enthusiasm. Conclusions Health education helps to enhance the personal value of undergraduates from eight-year program of clinical medicine, improves their communication skills, learning attitude, and comprehensive capacity to solve problems. It is a teaching method welcomed by children and their parents and unanimously accepted by clinical trainers.