This research enumerates the various parts of mathematical knowledge and summarizes the application of different mathematics contents in different medical professional courses.Then the distribution and consistency of medical students' scores in diagnostics, surgery and advanced mathematics are further analyzed. The results show that the scores of medical students in diagnostics, surgery and advanced mathematics are similar,the consistency coefficients of diagnosis, surgery and advanced mathematics are 0.412 and 0.530 respectively,and the u values are 8.606 and 10.932, all P＜0.01, which shows that the advanced mathematics scores are in moderate consistency with the other two medical courses,and the medical students' mastery of advanced mathematics affects the learning effect of the medical courses to some extent. On this basis,the author puts forward some measures to adjust the teaching contents according to the medical major demands and expert opinions,to promote the construction of the mathematics-medicine cases teaching method.To use the multimedia network teaching platform scientifically and rationally,so as to promote the reform in mathematics-related courses.