Objective To reform the traditional teaching pattern of Heart Failure theory by evaluating the application efficiency in the teaching of heart failure,which is the combination of micro-course with traditional teaching pattern.Methods Totally 232 five-year undergraduate students of eight classes of 2015 from Hunan University of Medicine,who major in clinical medicine,were randomly divided into experimental group and control group,with 116 students in total for each group.Apply the new teaching pattern which combined micro-course with traditional teaching to the experimental group on the lectures of Heart Failure.On the other hand,the traditional teaching pattern was adopted to the control group.Use the theoretical test method to understand the learning situation of the two groups.Employ questionnaire survey method to reveal the experimental group students' evaluation to the new teaching pattern which combined micro-course with traditional teaching.Results The average scores of the experimental group(75.34±8.86) in classroom examination was higher than the control group(65.28±8.04).There was a statistical significance between the two groups(t=9.06,P<0.01).Questionnaire indicated that students from the experimental group evaluate that the new teaching pattern combined micro-course with traditional stimalated thier interests and improved their capacity solve problems,make the key points convenient to memorize and activate classroom teaching.Conclusions The new teaching pattern combined micro-course with traditional teaching adapted to the characteristics of heart failure,which is an efficient and practical teaching method to stimulate the students' learning motivation and improve the teaching quality.