Objective To analyze the quantitative relationship between the medical school revenues and health expenditures,including the internal structures of them,and provide evidence to establish a stable guarantee mechanism for medical education funding in China. Methods Based on the data of all accredited American medical schools released by the Association of American Medical Colleges(AAMC),and the health expenditure data released with the Centers for Medicare and Medicaid Services(CMS) from 1980 to 2017,this study has analyzed the changes and relationship in the revenue structure of the U.S. medical schools and the health expenditure structure in the past nearly 40 years. Results Compared with the total annual health expenditure of US $ 3 trillion,the annual revenue of medical schools in the United States is about 100 billion US dollars.From 1980 to 2017 in medical schools in the United States,the average ratio of medical service revenue to personal health care expenditure was 2.2%(40.49/1879.93);the average ratio of federal scientific research funding income and health investment expenditure was 11.1%(13.6/122.43);the average ratio of total school revenues to total health expenditure is 3.4%(74.94/2 227.68). Conclusions Drawing on the experience of the United States,the government can broaden the funding channels for medical education and expand research funding in China's total health expenditure.Therefore we can establish a stable guarantee mechanism for medical education funding in China.