The purpose of professional base education is to help students quickly integrate into the new environment and develop good clinical work habits, which is an important component of standardized training for resident physicians. In order to improve the effectiveness of standardized training for resident physicians with different professional backgrounds in the field of anesthesia, the Anesthesia Department of West China Hospital began to reform the education in professional bases in 2019 through the design and implementation of modular and multi-mode teaching methods. The training content was divided into five modules: pre anesthesia visits, pre anesthesia preparation, intraoperative monitoring, equipment and skills, transportation and handover. Case based teaching and simulation teaching were comprehensively applied standardized patient training and other various training modes. After the training, satisfaction surveys and theoretical exams were conducted on the 98 trainees. More than 90.0% of the trainees believed that the setting of the five modules was necessary, and the exam score was (79.56±3.84), which met the requirements of anesthesia for theoretical knowledge at the beginning of clinical work. The modular and multi-mode integration into professional base education has played a good role in improving the theoretical level of anesthesia and implementing training requirements for students.