Clinical probation, as a bridge to link preclinical medical theory and clinical training, is of great significance for medical students training. The combined teaching method of flipped classroom with team-based learning (TBL) has changed the previous “quick observer” clinical internship. It is important for stimulating students' learning initiative and team spirit. This article discusses the teaching method of flipped classroom combined with TBL in the respiratory internal medicine internship for medical students from the class taught in English as teaching language enrolled in 2015 in Jinzhou Medical University, so as to improve the students' capacity building in autonomous and teamwork, and the training of clinical reasoning, so as to reach the goal of qualified medical education.