Considering medical education as a whole, according to the overall requirements and standards of curriculum ideology and politics, Hubei University of Medicine has reshaped the “three-dimensional” ideological and political objectives of basic medicine curriculum with the discipline group of basic medicine as the starting point, to establish a library of curriculum ideological and political elements with the unity of “six perspectives” homogenization and personalization, and built a three-dimensional way to realize the integration and connection of professional curriculum content and curriculum ideology and politics. It has achieved the goal of ideological and political education in the integrated curriculum of “integration of five education”. The construction of the curriculum ideological and political system has achieved good results. The research results of the 2019-2021 academic year show that more than 90% of students recognize and accept the system and are conducive to the creation of new values, and more than 70% of students believe that the system can promote and expand the learning of professional courses. The implementation of the ideological and political system of basic medical subject group courses is an effective exploration of carrying out ideological and political education in medical professional courses, and can provide reference for the ideological and political construction of medical colleges and universities.