The online teaching with situational-based learning method is aiming at attracting every student to join the learning process. It's easier for international students to master new knowledge. This research took the teaching of histology and embryology for six-year program internatiomal students majoring in clinical medicine,enrolled in 2019 in Shanxi Medical University as an example during the prevention and control of COVID-19 pandemic. The teaching effect was evaluated by questionnaire survey, process assessment and summative test. The examination results showed that the passing rate of students' process assessment was 93.7% (74 /79) and the excellent rate was 79.7% (63/79). However, the passing rate of students' summative test was only 12.7% (10/79) and the excellent rate was 3.8% (3/79). Totally 86.6% (58/ 67) of the international students believed that the online teaching with a situation-based method was helpful for their active thinking. The situation-based online teachingis helpful for the students to participate in the classroom and the cultivation of their active thinking ability, but how to supervise the students to arrange the review reasonably after the online course and improve the results of students' summative test is a challenge to tackle with more research.