Health and society is a new and comprehensive course module set up as a component in Shantou University Medical College. The module breaks through the traditional discipline system which separates basic medicine and clinical medicine, clinical medicine and preventive medicine. With the “one health” as the core and the bio-psycho social medical model as the main line, this project designs the curriculum containing six parts: social factors and health, psychological factors and health, natural factors and health, biological factors and health, health services and health, health education and health promotion. The course module aims at promoting the integration, intersection and penetration of preventive medicine, clinical medicine and other disciplines, strengthens the cultivation of the overall health awareness of medical students. In order to review and summarize the module implementation, the students who are one the way of learning in this module and those who have already completed the module learning are investigated to understand the learning outcomes and potential influence to learners' attitude. As result of investigation shows, this course has a significant effect on students and also shows direction and space of further improvement.