Ultrasound diagnosis and ultrasound-guided operation are essential skills required for modern vascular surgeons. Case-based learning (CBL) has been implemented widely in medical education to engage students and build their capacity to analyze and solve problems using basic knowledge. The case-based training of ultrasonic diagnosis and ultrasound-guided operation for vascular surgeon residents were reported as examples to illustrate the design and implementation of comprehensive ultrasound education. The teaching was implemented in a modular mode. Clinical application tests corresponding to each modular, questionnaires survey and workshops were used to evalute and analyze the teaching results. Results suggested that all students achieved excellent clinical testing scores (scored over 90) in module elementary ultrasonic teaching and clinical practice of ultrasound. As shown in the questionnaires, all the students recognized the positive effect of the education program in terms of stimulating learning interests and being well trained in diagnostic and operational skills in a short-term course. The comprehensive case based ultrasound technology training is proven to be advantageous to improve the training of ultrasound techniques for lower extremity venous diseases among vascular surgeons and recognized by all surgery specialists.